...Inflammation Is the Result of a Multi-faceted ProcessHormonal changes are at the root of acne pathogenesis.The primary target of acne is the pilosebaceous unit of the follicle.Hormones stimulate increased production of lipids in the follicle.Inflammation probably arises from the presence of prostaglandins and cytokines that are attracted to the lipids within the follicle.Some individuals may be genetically prone to overactive inflammatory pathways, which increases their chances of having severe inflammatory acne....»
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 «...A blackhead is when the pores that are close to the surface clog up with bacteria, dirt, and dead skin cells. If the pore is open, and the dirt and oil is exposed to the air, it reacts to the oxygen turning the inflammation into a dark-colored blackhead. It is the dirt, bacteria and skin cells that keep the oil from flowing to the surface of the skin causing this condition....»
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